Anti-LMNA Mouse T4 Antibody [clone: 4C4]

Lieferant: Biosensis
M-1689-100
BSENM-1689-100EA 312 EUR
BSENM-1689-100
Anti-LMNA Mouse T4 Antibody [clone: 4C4]
Antikörper
The Lamin proteins are members of the intermediate filament protein family but are located inside the nucleus rather than in the cytoplasm. The lamins function as skeletal components tightly associated with the inner nuclear membrane. Originally the proteins of the nuclear cytoskeleton were named Lamin A, B and C, from top to bottom as visualized on SDS-PAGE gels. Subsequently it was found that Lamins A and C were coded for by a single gene, while the Lamin B band may contain two proteins encoded by two genes now called Lamin B1 and Lamin B2. Lamin A has a mass of about 74kDa while Lamin C is 65kDa. The Lamin A protein includes 98 amino acids missing from Lamin C, while Lamin C has a C-terminal 6 amino acid peptide not present in Lamin A. Apart from these regions Lamin A and C are identical so that antibodies raised against either protein are likely to cross react with the other, as is the case with this monoclonal.
Application information:
Immunocytochemistry (ICC), Western Blotting (WB) and Flow Cytometry (~2 ug per 10^6 cells). A dilution of 1:1,000-1:2,000 is recommended for WB. A dilution of 1:500-1:1,000 is recommended for ICC. The optimal dilution should be determined by the end user.

Type: Primary
Antigen: LMNA
Clonality: Monoclonal
Clone: 4C4
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: Human
Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR