Mouse;Rat obestatin
Lieferant: ENZO LIFE SCIENCES
ALX164005M001
ENZOALX164005M001EA
239
EUR
ENZOALX164005M001
Mouse;Rat obestatin
Proteine und Peptide
Food intake modulator
Obestatin derives like ghrelin from proghrelin, but exhibits opposite physiological effects. Obestatin decreases food intake and body weight in rodents. Moreover, obestatin also counteracts ghrelin’s effect by decelerating gastric emptying and decreasing intestinal contractility. Obestatin binds to orphan G protein-coupled receptor GPR39. Amidation of the C-terminus seems to be important for obestatin’s activity.
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