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Beschreibung: Cell permeable inhibitor of the 26S proteasome (MCP; multicatalytic proteinase complex) in HT4 cells. Causes accumulation of ubiquitinylated proteins in neuronal cells. Prevents the activation of NF-κB in response to TNF-α or okadaic acid through inhibition of IκBα degradation.

Artikel-Nr: (ENZOALX550396M005)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: TRP channel agonist.

VE: 1 * 5 mg

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: For the detection of apoptotic cells by flow cytometry.

Artikel-Nr: (ENZOENZ52309)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Positively charged rhodamine dyes (such as rhodamine esters and rosamines) are selectively localized in mitochondria, thus they are widely used for labeling mitochondria of live cells. Like JC-1,TMRE is widely used for measuring mitochondrial membrane potential, in addition to selectively staining mitochondria. Real-time imaging of mitochondrial membrane potential in individual cardiomyocytes within perfused rat hearts has been demonstrated with this dye, using 2-photon laser-scanning microscopy.

VE: 1 * 25 mg

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Osteopontin (OPN) is an acidic extracellular matrix cell adhesion protein that is relatively abundant not only in bone matrix, plasma, urine, and milk, but is also found in malignant and atherogenic tissues. Phosphorylation, glycosylation and calcium modifications allow intact and fragmented Osteopontin to direct a variety of diverse responses including tissue remodeling, inflammation and cell survival. Plasma Osteopontin has been shown to provide prognostic information in breast, prostate, colon, and lung cancers as well as metastatic carcinomas. The notable presence of Osteopontin in a variety of tumors is strongly correlated to pathological stage, suggesting its critical role in tumor invasiveness, progression and metastasis. In addition, Osteopontin inhibits inducible nitric oxide synthase activity, thereby protecting tumor cells from NO-mediated macrophage cytotoxic attack. Osteopontin is found in atherosclerotic plaques and may drive a number of diabetic vascular pathologies.

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Inhibitor of caspase-1 and -4

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Potent and selective serotonin uptake inhibitor

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Produced in <i>E. coli</i>.

Artikel-Nr: (ENZOENZABS2500100)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Recommended Applications: IF

Species reactivity: Human, Dog

VE: 1 * 100 µG

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Apoptosis inducer.

Artikel-Nr: (ENZOALX210537R100)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: CD51 (integrin αV subunit) associates with CD61 (integrin β3 subunit) binding to the RGD sequence in extracellular matrix proteins like vitronectin, fibrinogen, thrombospondin, von Willebrand factor and osteopontin. The αV/β3 heterodimer is expressed in endothelial cells, leukocytes, NK cells, macrophages, neutrophils, platelets and several malignant tumor cells and seems to play a role in embryo implantation, angiogenesis, wound healing and cancer. αV/β3  is also highly expressed in osteoclasts being important for bone resorption.

VE: 1 * 100 µl

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Artikel-Nr: (ENZOBMLPG0050010)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Prostanoid receptor ligand.

VE: 1 * 10 mg

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Artikel-Nr: (ENZOADI908066010)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Produced in <i>E.coli</i>.

VE: 1 * 10 µG

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Artikel-Nr: (ENZOALX522044C050)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Produced in HEK 293 cells. The cysteine-rich domain of human NGFR (nerve growth factor receptor; p75NTR) (aa 1-250) is fused to the Fc portion of human IgG1.

VE: 1 * 50 µG

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Artikel-Nr: (ENZOBMLEI1080100)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Potent and selective inhibitor of microsomal and cytosolic epoxide hydrolase (IC50=68 nM). Inhibits epoxide hydrolysis of epoxyeicosatrienoic acids.

VE: 1 * 100 mg

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Anti-HSP90 Mouse Monoclonal Antibody [clone: 2D11B9]