CGP 74514A
Lieferant: ENZO LIFE SCIENCES
ALX270391M005
ENZOALX270391M005EA
135
EUR
ENZOALX270391M005
CGP 74514A
CGP 74514A
Cell permeable, potent and selective inhibitor of CDK1/cyclin B (IC50=25 nm). Reported to affect the activities of other kinases only at much higher concentrations: PKCα (IC50=6.1 nm), PKA (IC50=125 µm) and EGFR (IC50>10 µm). Induces mitochondrial damage and apoptosis in several human leukemia cell lines (>3 µm).
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