EX 527 ≥95%

Lieferant: ENZO LIFE SCIENCES

Synonyme: 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide, EX-527, Selisistat

ALX270437M001
ENZOALX270437M001EA 193 EUR
ENZOALX270437M001
EX 527 ≥95%
EX 527

Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48µM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100µg). Inhibits the deacetylation of p53 (IC50=1µM).


  • SIRT inhibitor


White to beige powder.


Soluble in DMSO (10 mg/ml).

Formel: C₁₃H₁₃ClN₂O
Molecular Weight: 248,71 g/mol
Lagertemperatur: Gefrierschrank
MDL: MFCD03009471
CAS-Nummer: 49843-98-3

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