AMI-1 ≥98% (durch 1H-NMR, HPLC)

Lieferant: ENZO LIFE SCIENCES

Synonyme: AMI 1, Sodium 7,7'-(carbonylbis(azanediyl))bis(4-hydroxynaphthalene-2-sulphonate), 7,7'-(Carbonyldiimino)bis[4-hydroxy2-naphthalenesulphonicacid]disodiumsalt, 7,7′-Carbonylbis(azanediyl)bis(4-hydroxynaphthalene-2-sulfonic acid) sodium salt, AMI-1 sodium salt

ALX270440M005
ENZOALX270440M005EA 157 EUR
ENZOALX270440M005
AMI-1 ≥98% (durch 1H-NMR, HPLC)
AMI-1

PRMT inhibitor


Potent, cell permeable and specific inhibitor of protein arginine N-methyltransferases (PRMTs) (IC50=8.8µM for human PRMT1 and 3.0µM for yeast Hmt1p). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Exhibits only minimal effects on lysine N-methyltransferases. Suppresses the transcriptional coactivator activity of PRMT1 and PRMT4. Inhibitor of HIV-1 RT polymerase (IC50=5.0µM).

Formel: C₂₁H₁₄N₂Na₂O₉S₂
MDL: MFCD00068249
CAS-Nummer: 20324-87-2 | 134-47-4 (free base)

Bestellen


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR