CDK1/2 Inhibitor III ≥95% (durch HPLC)

Lieferant: ENZO LIFE SCIENCES

Synonyme: 5-Amino-3-((4-(aminosulphonyl)phenyl)amino)-N-(2,6-difluorophenyl)-1H-1,2,4-triazole-1-carbothioamide

ALX270442M001
ENZOALX270442M001EA 307 EUR
ENZOALX270442M001
CDK1/2 Inhibitor III ≥95% (durch HPLC)
CDK1/2 Inhibitor III

Cell permeable triazolo-diamine compound that displays anti-proliferative properties in various human cancer cells (IC50=20nM, 35nM and 92nM in HCT-116, HeLa, and A375 cells). Acts as a highly potent, ATP-competitive inhibitor of CDK1/cyclin B and CDK2/cyclin A (IC50=600pM and 500pM) with selectivity over VEGF-R2 and GSK-3β (IC50=32nM and 140nM).


White to off-white solid.


Soluble in DMSO (10mg/ml), tetrahydrofuran or acetone.

Formel: C₁₅H₁₃F₂N₇O₂S₂
Molecular Weight: 425,4 g/mol
Lagertemperatur: Gefrierschrank
CAS-Nummer: 443798-55-8

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