SMI-4a ≥95%
Lieferant: ENZO LIFE SCIENCES
Synonyme:
Pim Inhibitor 4a, 5-(3-(Trifluoromethyl)benzylidene)thiazolidine-2,4-dione, (5Z)-5-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione, TCS-PIM-1-4a, (Z)-5-(3-Trifluoromethylbenzylidene)thiazolidine-2,4-dione
Pim1 inhibitor
Selective inhibitor of Pim-1 and Pim-2 protein kinases. Inducer of G1 phase cell cycle arrest. Inducer of p27Kip1. Inducer of apoptosis through the mitocondrial pathway. Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway. Downregulates c-myc. Inhibitor of PRAS40 phosphorylation and mTOR activity. Potential anti-cancer compound. Blocks prostate cancer growth.
Formel:
C₁₁H₆F₃NO₂S Molecular Weight: 273,23 g/mol |
MDL:
MFCD01152003 CAS-Nummer: 327033-36-3 |
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