Sauchinone

Lieferant: ENZO LIFE SCIENCES

Synonyme: 1′-Epimer dihydrocarpanone, (5aR,5a1R,7R,8S,8aR,14aS)-7,8-Dimethyl-5a,5a1,6,7,8,8a-hexahydro-5H-benzo[kl]bis([1,3]dioxolo)[4,5-b:4',5'-g]xanthen-5-one

ALX350116M005
ENZOALX350116M005EA 345 EUR
ENZOALX350116M005
Sauchinone
Sauchinone

Cytoprotective and antioxidant


Diastereomeric lignan with cytoprotective and antioxidant activities in cultured hepatocytes. Inhibitor of LPS-inducible iNOS (NOS II), TNF-alpha and COX-2 expression in macrophages through suppression of IkappaBalpha phosphorylation and p65 nuclear translocation and of C/EBP and/or AP-1 activation, which may have constitutive anti-inflammatory effects. Suppressor of NF-kappaB by inhibiting transactivation activity of the RelA subunit. Inhibits staurosporine (Prod. No. ALX-380-014)-induced apoptosis. Inhibits RANKL-induced osteoclastogenesis by reducing ROS generation.


Isolated from Saururus chinensis.

Formel: C₂₀H₂₀O₆
Molecular Weight: 356,4 g/mol
MDL: MFCD08702698
CAS-Nummer: 177931-17-8

Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR