(-)-Arctigenin (aus Arctium lappa) ≥97% (durch HPLC)
Lieferant: ENZO LIFE SCIENCES
Synonyme:
Arctigenin, (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone, (3R,4R)-4-(3,4-Dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one
Lignan derivative, which shows antitumor, anti-inflammatory, immunomodulatory and neuroprotective activities. Down-regulates anti-apoptotic protein Bcl-XL. Potent inhibitor of HIV type-I integrase and DNA topoisomerase II. Shows phytoestrogenic and cytotoxic properties against Hep62 cells. Antagonist for platelet activating factor and Ca²⁺. Blocks the activation of Akt (protein kinase B; PKB) induced by glucose starvation.
- Antitumor agent
Colorless crystals.
Soluble in DMSO (34mg/ml, heating, sonication); sparingly soluble in water.
Formel:
C₂₁H₂₄O₆ Molecular Weight: 372,4 g/mol Lagertemperatur: Gefrierschrank |
MDL:
MFCD00870597 CAS-Nummer: 7770-78-7 |
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