Galiellalactone (aus unidentified fungus MST-FP1888) ≥95% (durch HPLC)
Lieferant: ENZO LIFE SCIENCES
Synonyme:
NSC-645020, (7bS)-5,5aR,6,7,7aR,7b-hexahydro-7b-hydroxy-4S-methyl-indeno[1,7-bc]furan-2(4H)-one
Originally isolated from Galiella rufa as a plant growth regulator. Inhibits IL-6 mediated signal transduction by blocking the binding of the activated STAT3 dimers to their DNA binding sites without inhibiting the tyrosine and serine phosphorylation site of the STAT3 transcription factor.
- STAT3 inhibitor
White to light tan solid.
Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
Formel:
C₁₁H₁₄O₃ Molecular Weight: 194,23 g/mol Lagertemperatur: Gefrierschrank |
CAS-Nummer:
133613-71-5 |
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