Fostriecin sodium salt (aus Streptomyces pulveraceous subsp. fostreus) ≥98% (durch HPLC)
Lieferant: ENZO LIFE SCIENCES
Synonyme:
(6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt, Fostriecin
Antitumor antibiotic. Catalytic inhibitor of topoisomerase II. Strong protein phosphatase 2A (PP2A) inhibitor (IC50=3.2nM). Weak inhibitor for PP1 (IC50=131µM). No apparent effect on PP2B. The binding site for fostriecin on PP2A is different from that of okadaic acid.
Colorless solid
Soluble in water (50 mg/mL), methanol (10 mg/mL) or 100% ethanol (10 mg/mL)
Verpackung: Shipping temperature: Ambient
Formel:
C₁₉H₂₆O₉PNa Lagertemperatur: Gefrierschrank |
CAS-Nummer:
87860-39-7 |
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