Idarubicin hydrochloride ≥98% (durch HPLC)
Lieferant: ENZO LIFE SCIENCES
Synonyme:
4-Demethoxydaunorubicin, DMDR, Idamycin, Idarubicin HCl, (7S,9S)-9-Acetyl-7-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride
More potent, lipophilic and antineoplastic analog of daunorubicin. DNA-damaging effect includes DNA oxidation and methylation, DNA intercalation, inhibition of DNA synthesis, induction of DNA strand breaks and delay of cell cycle progression. Inhibitor of topoisomerase IIα. Produces endonucleolytic cleavage and is a marker of apoptosis.
- Topoisomerase IIα inhibitor
Orange crystalline solid.
Soluble in water or methanol.
Formel:
C₂₆H₂₇NO₉·HCl Molecular Weight: 497,5 · 36,5 g/mol Lagertemperatur: Gefrierschrank |
MDL:
MFCD00897212 CAS-Nummer: 57852-57-0 |
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