Tranilast ≥95% (durch HPLC)

Lieferant: ENZO LIFE SCIENCES

Synonyme: 2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic Acid, 2-(3-(3,4-Dimethoxyphenyl)acrylamido)benzoic acid, N-(3,4-Dimethoxycinnamoyl)anthranilic Acid

ALX550409M010
ENZOALX550409M010EA 83.6 EUR
ENZOALX550409M010
Tranilast ≥95% (durch HPLC)
Tranilast

Anti-inflammatory and anti-angiogenic


Anti-inflammatory and anti-angiogenic agent. Inhibits VEGF-induced angiogenesis in vivo . Inhibits proliferation and tube formation of human endothelial cells in vitro. Also inhibits smooth muscle cell proliferation and prevents post-angiplasty retsenosis.Synthetic compound with structural similarity to the tryptophan (Trp) catabolites kynurenines. Tranilast ameliorates the disease severity in animal models of multiple sclerosis, in part, by inducing T cell tolerance. Trp degradation is an important mechanism in the maintenance of T cell tolerance in a variety of disease models and is mediated by the rate limiting enzyme indoleamine 2,3-dioxygenase (IDO).

Formel: C₁₈H₁₇NO₅
Molecular Weight: 327,34 g/mol
MDL: MFCD00864787
CAS-Nummer: 53902-12-8

Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR