Fenobam ≥98% (durch 1H-NMR)
Lieferant: ENZO LIFE SCIENCES
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Gefahr
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Synonyme:
1-(3-Chlorophenyl)-3-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)urea
mGluR5 antagonist.
Potent and selective non-competitive mGluR5 antagonist that displays inverse agonist properties; blocks mGluR5 constitutive activity in vitro (IC50=87 nM).
Acts at an allosteric modulatory site shared with MPEP and binds mGluR5 with Kd values of 54 nM and 31 nM for rat and human receptors respectively. Displays anxiolytic activity following oral administration in vivo.
Soluble in DMSO or methanol.
Formel:
C₁₁H₁₁ClN₄O₂ Molecular Weight: 266,7 g/mol Lagertemperatur: Kühlschrank |
MDL:
MFCD00868019 CAS-Nummer: 57653-26-6 UN: 2811 ADR: 6.1,III |
Spezifikation Testergebnisse
Purity (¹H-NMR) | ≥98% |
Identity | Determined by NMR |
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