G-type-iODN
Lieferant: ENZO LIFE SCIENCES
TLR9 inhibitor
Inhibitory iODN oligodeoxynucleotide with phosphorothioate backbone. Potent sequence of an inhibitory ODN based on poly-G class I sequences targeting TLR9, but without additional effect on TLR7 and TLR8 signaling, for in vivo use in rodents (50-150 µg per injection). For active CpG compounds see e.g. ODN 1668 (Prod. No. ALX-746-001).
Synthetic.
Bestellinformation: Quantity: ~15 nmol (100 µg). Sufficient for ~100 cellular inhibition assays. Working concentration depends upon concentration, type and MW of stimulating CpG ODN, the cellular system and read-out used. Titrate at 3-5 fold molar excess for inhibition.
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