Aphidicolin ≥98% (durch TLC)
Lieferant: ENZO LIFE SCIENCES
Synonyme:
(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-Bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol
Reversible inhibitor of DNA polymerase a and d
A diterpene fungal metabolite that acts as reversible inhibitor of eukaryotic nuclear DNA replication. Useful for cell synchronization. Blocks the cell cycle at early S phase. Prolongs the half life of DNA methyltransferase. Specific inhibitor of DNA polymerase α and δ in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer.
Formel:
C₂₀H₃₄O₄ Molecular Weight: 338.488 g/mol |
MDL:
MFCD00083214 CAS-Nummer: 38966-21-1 |
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