Baicalein ≥98% (durch TLC)

Lieferant: ENZO LIFE SCIENCES

Synonyme: 5,6,7-Trihydroxy-2-phenylchromen-4-on, 5,6,7-Trihydroxyflavon

BMLEI1060050
ENZOBMLEI1060050EA 361 EUR
ENZOBMLEI1060050
Baicalein ≥98% (durch TLC)
Baicalein

Lipoxygenase inhibitor


Inhibits cellular Ca2+ uptake and calcium mobilization. Inhibitor of protein tyrosine kinase in leukemia (CEM) cells. Induces cell cycle arrest and apoptosis. Anti-inflammatory compound. Has anti-thrombotic, anti-proliferative and anti-mitogenic effects.Originally reported as a selective inhibitor of 12-lipoxygenase, baicalein has since been shown to inhibit both 12-LO and 15-LO (IC50=0.64µM for 12-LO and 1.6µM for 15-LO). Inhibits leukotriene biosynthesis (at higher concentrations) and release of lysosomal enzymes. Inhibits adjuvant-induced arthritis. Also inhibits prolyl oligopeptidase (POP/PREP)(IC50=36µM).

Formel: C₁₅H₁₀O₅
Molecular Weight: 270,24 g/mol
MDL: MFCD00017459
CAS-Nummer: 491-67-8
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=1b20c55630ac1375c425f570fc4fed1bfc99e885&vid=c959da995a9d69eacfbe28e3244bd37454493182&prid=web&clid=SAPDAM

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