Erbstatin analog ≥98% (durch TLC)
Lieferant: ENZO LIFE SCIENCES
Synonyme:
Erbstatin Analog, 2,5-Dihydroxycinnamic acid methyll ester, Methyl 2,5-Dihydroxycinnamate, Methyl 3-(2,5-dihydroxyphenyl)acrylate
EGFR inhibitor
Erbstatin is a novel inhibitor of the EGF receptor-associated tyrosine kinase. It is an unstable compound and is completely inactivated in serum in 30 minutes. Methyl 2,5-dihydroxycinnamate is a stable erbstatin analog retaining activity after a 60 minute incubation. It inhibits EGF receptor-associated tyrosine kinase in vitro (IC50=0.77 µM). Inhibition is competitive with substrate and noncompetitive with ATP.
Formel:
C₁₀H₁₀O₄ Molecular Weight: 194,19 g/mol |
MDL:
MFCD00132932 CAS-Nummer: 63177-57-1 |
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