trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine hydrochloride ≥98% (by UHPLC)
Lieferant: ENZO LIFE SCIENCES
Synonyme:
Terbinafine Hydrochloride, Terbinafine HCl, (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride
Inhibits ergosterol biosynthesis at the level of squalene epoxidase. Potent non-competitive inhibitor of squalene epoxidase from Candida (Ki=30 nM), inhibiting mammalian enzymes at higher concentrations (4-77 µM). It inhibits HUVEC proliferation and angiogenesis and displays interesting anti-inflammatory and free radical scavenging activities. Clinically useful antifungal agent.
- Squalene epoxidase inhibitor
White to off-white solid.
Soluble in ethanol (45 mg/ml), DMSO (30 mg/ml) or water (3 mg/ml).
Formel:
C₂₁H₂₅N Molecular Weight: 327,90 g/mol Lagertemperatur: Raumtemperatur |
MDL:
MFCD00145430 CAS-Nummer: 78628-80-5 |
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