trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine hydrochloride ≥98% (by UHPLC)

Lieferant: ENZO LIFE SCIENCES

Synonyme: Terbinafine Hydrochloride, Terbinafine HCl, (E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride

BMLEI3180100
ENZOBMLEI3180100EA 86.9 EUR
ENZOBMLEI3180100
trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine hydrochloride ≥98% (by UHPLC)
trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine hydrochloride

Inhibits ergosterol biosynthesis at the level of squalene epoxidase. Potent non-competitive inhibitor of squalene epoxidase from Candida (Ki=30 nM), inhibiting mammalian enzymes at higher concentrations (4-77 µM). It inhibits HUVEC proliferation and angiogenesis and displays interesting anti-inflammatory and free radical scavenging activities. Clinically useful antifungal agent.


  • Squalene epoxidase inhibitor


White to off-white solid.


Soluble in ethanol (45 mg/ml), DMSO (30 mg/ml) or water (3 mg/ml).

Formel: C₂₁H₂₅N
Molecular Weight: 327,90 g/mol
Lagertemperatur: Raumtemperatur
MDL: MFCD00145430
CAS-Nummer: 78628-80-5
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