DuP-697 ≥98% (durch TLC)

Lieferant: ENZO LIFE SCIENCES

Synonyme: 5-bromo-2-(4-fluorophenyl)-3-(4-(methylsulphonyl)phenyl)-thiophene

BMLEI3580005
ENZOBMLEI3580005EA 164 EUR
ENZOBMLEI3580005
DuP-697 ≥98% (durch TLC)
DuP-697

DuP-697 is a highly selective and irreversible inhibitor of cyclooxygenase-2 (COX-2). (COX-2 IC50=10 nm, COX-1 IC50=800 nm). It is an orally effective anti-inflammatory, analgesic and antipyretic agent which is not ulcerogenic. Inhibition of COX-2 by DuP-697 and other inhibitors exacerbates ischemia-induced myocardial dysfunction in the rabbit. It inhibits angiogenesis and induces apoptosis in human endothelial cells.

Formel: C₁₇H₁₂BrFO₂S₂
Molecular Weight: 411,3 g/mol
CAS-Nummer: 88149-94-4
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=34005c263e21d0b8754e5c67ca25860e5dcf2d1b&vid=99df98b024c2d65c997716a427ef15839bc35bcf&prid=web&clid=SAPDAM

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