PD 98059 ≥95% (durch HPLC)

Lieferant: ENZO LIFE SCIENCES

Synonyme: PD98059, 2'-Amino-3'-methoxyflavone, 2-(2-Amino-3-methoxyphenyl)chromone, PD 98059, 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one, 2-(2-Amino-3-methoxyphenyl)-4H-chromen-4-one

BMLEI3600005
ENZOBMLEI3600005EA 114 EUR
ENZOBMLEI3600005
PD 98059 ≥95% (durch HPLC)
PD 98059

PD-98059 is a potent and selective inhibitor of MAP kinase kinase (MEK). It selectively blocks the activation of MEK thereby inhibiting the phosphorylation and the activation of MAP kinase. PD-98059 is cell permeable. In PC12 pheochromocytoma cells, it completely blocked the increase in MAP kinase activity produced by NGF, IC50=2µM. Enhances self-renewal of embryonic stem cells PD-98059 is an invaluable tool to help elucidate the role of the MAPK cascade in a variety of biological systems. Inhibits cell growth and proliferation in acute myelogenous leukemia cell lines by causing cell arrest.


  • MEK inhibitor


Pale yellow solid


Soluble in DMSO (6.5mg/ml); 25mg/ml in anhydrous DMSO), methanol, dichlormethane and 100% ethanol (0.6mg/ml).

Formel: C₁₆H₁₃NO₃
Molecular Weight: 267,284 g/mol
Lagertemperatur: Gefrierschrank
MDL: MFCD00671789
CAS-Nummer: 167869-21-8
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