BML-277 Chk2 inhibitor ≥98% (durch TLC)
Lieferant: ENZO LIFE SCIENCES
Synonyme:
BML-277, 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzo[d]imidazole-6-carboxamide, 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide, Chk2 Inhibitor II
BML-277 is a highly selective inhibitor of Chk2 (IC50=15nM). It displays potent radioprotective activity and prevents apoptosis of human T cells subjected to ionizing radiation (EC50= 3-7.6µM). Useful tool for dissecting the role of Chk2 in cellular signaling.
- Chk inhibitor
Off-white solid.
Soluble in DMSO (20mg/ml) or ethanol (20mg/ml).
Formel:
C₂₀H₁₄ClN₃O₂ Molecular Weight: 363,8 g/mol Lagertemperatur: Gefrierschrank |
MDL:
MFCD08276917 CAS-Nummer: 516480-79-8 |
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