SEW-2871 ≥98%

Lieferant: ENZO LIFE SCIENCES

Synonyme: 5-(4-Phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole, 5-[4-Phenyl-5-(trifluoromethyl)thiophen-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole, SEW2871

BMLLP1060050
ENZOBMLLP1060050EA 299 EUR
ENZOBMLLP1060050
SEW-2871 ≥98%
SEW-2871

SEW-2871 is a novel, potent EDG receptor agonist structurally unrelated to sphingosine-1-phosphate and is highly selective for the human S1P1 receptor. It inhibits lymphocyte recirculation in vivo and produces immunosuppression without associated bradycardia which is induced by other less selective S1P agonists. In mice SEW-2871 blocked TNFα induced monocyte adhesion to endothelium.


  • S1P receptor ligand


White solid.

Formel: C₂₀H₁₀F₆N₂OS
Molecular Weight: 440,4 g/mol
Lagertemperatur: Raumtemperatur
MDL: MFCD00096600
CAS-Nummer: 256414-75-2
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=673d1e403f3f24384c70a46bdd3e7a84a0590a1d&vid=9525e7807ba310030bc3f4d9d81fd8aec59ac2d1&prid=web&clid=SAPDAM

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