CaM kinase II (281-309)

Lieferant: ENZO LIFE SCIENCES

BMLP2010500
ENZOBMLP2010500EA 366 EUR
ENZOBMLP2010500
CaM kinase II (281-309)
Proteine und Peptide

CaM kinase inhibitor


Sequence is from Ca²⁺/calmodulin-dependent kinase A subunit negative regulatory sequence containing the calmodulin binding site (290-309) plus autophosphorylation site (Thr286). Peptide can be phosphorylated at Thr286 by PKC. Useful as a CaM binding peptide and inhibits CaMKII by blocking Ca²⁺/CaM activation and the enzyme active-site. IC50=80 nM, CaM binding; IC50=2 µM, active-site.

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