ADAM Substrate

Lieferant: ENZO LIFE SCIENCES

BMLP2350001
ENZOBMLP2350001EA 234 EUR
ENZOBMLP2350001
ADAM Substrate
Proteine und Peptide

Fluorogenic substrate for ADAM8 (kcat/Km = 1,0×105 M-1s-1), ADAM10 (6,2×103), ADAM12 (2,8×105), TACE (TNF-α converting enzyme, ADAM17) (4,3×105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485 nm, Em.: 530 nm. This substrate is useful for inhibitor screening and kinetic analysis.


Bestellinformation: Quantity: 1 mg net peptide.

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