Prostaglandin A2 ≥99% (durch TLC)
Lieferant: ENZO LIFE SCIENCES
Synonyme:
Medullin, PGA2, Prosta-5,10,13-trien-1-oic acid, 15-hydroxy-9-oxo-, (5Z,13E,15S)-
Blocks cell cycle at the G1 and G2/M phase [1] by inhibiting G1 phase cyclin dependent kinases [2] downregulating cyclin D1 [3]. Modulates all three aspects of the glutathione-mediated biotransformation system, i.e. GSH levels, glutathione S-transferase activity and transport of GSH conjugates [4]. Antitumor activity. Induces γ-glutamylcysteine synthetase and apoptosis in L-1210 cells.
- CDK inhibitor
Neat oil.
Soluble in 100% ethanol, acetone or ethyl acetate.
Formel:
C₂₀H₃₀O₄ Molecular Weight: 334,5 g/mol Lagertemperatur: Gefrierschrank |
CAS-Nummer:
13345-50-1 |
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