Cytochalasin B ≥98%
Lieferant: ENZO LIFE SCIENCES
Synonyme:
7(S),20(R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,23-dione
Ultra-pure; inhibits actin polymerization
Cytochalasin B is a cell-permeable fungal toxin which binds to the barbed end of actin filaments inhibiting both the association and dissociation of subunits. It causes the disruption of actin filaments and inhibition of actin polymerization. It also inhibits monosaccharide transport across cell membranes. inhibits glucose transport and platelet aggregation. Blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL-60 cells.
Isolated from Drechslera dematoidea
Formel:
C₂₉H₃₇NO₅ Molecular Weight: 479,62 g/mol |
MDL:
MFCD00077704 CAS-Nummer: 14930-96-2 |
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