JC-1 (iodide) ≥95% (durch HPLC), ultrarein

Lieferant: ENZO LIFE SCIENCES

Synonyme: JC1, 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine iodide, 1,1',3,3'-tetraethyl-5,5',6,6'-tetrachloroimidacarbocyanine iodide, 5,5’,6,6’-Tetrachloro-1,1’,3,3’-tetraethylbenzimidazolylcarbocyanine iodide

ENZ52304
ENZOENZ52304EA 284 EUR
ENZOENZ52304
JC-1 (iodide) ≥95% (durch HPLC), ultrarein
JC-1 (iodide)

Mitochondria dye


JC-1 is widely used for determining mitochondrial membrane potential by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-1 accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (590 nm) in healthy cells. However, upon cell injury, as membrane potential decreases, JC-1 monomers are generated, resulting in a shift to green emission (529 nm). The principal advantage of JC-1 relative to other commonly employed fluorescent probes of mitochondrial membrane potential is that it allows for both qualitative visualization, considering the shift from orange to green fluorescence emission, and quantitative detection, considering the fluorescence intensity ratio. Wavelength Maxima: Excitation 515 nm, Emission 529 nm.

Formel: C₂₅H₂₇Cl₄IN₄
Molecular Weight: 652,223 g/mol
Lagertemperatur: Gefrierschrank
MDL: MFCD00188475
CAS-Nummer: 3520-43-2
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