Hydrogenchlorid --N-(3-ethinylphenyl)-6,7-bis(2-methoxyethoxy)-4-chinazolinamin ≥95% (durch HPLC)
Lieferant: ENZO LIFE SCIENCES
Synonyme:
Erlotinib Hydrochloride
ENZCHM1570050
ENZOENZCHM1570050EA
227
EUR
ENZOENZCHM1570050
Hydrogenchlorid --N-(3-ethinylphenyl)-6,7-bis(2-methoxyethoxy)-4-chinazolinamin ≥95% (durch HPLC)
N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride
EGFR tyrosine kinase auto-phosphorylation inhibitor
Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC50 of 2 nM against EGFR. It is >1000-fold more sensitive for EGFR than for c-Src or v-Abl.
Formel:
C₂₂H₂₄ClN₃O₄ Molecular Weight: 429,901 g/mol |
MDL:
MFCD07781272 CAS-Nummer: 183319-69-9 |
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