Anti-ANO1 Mouse Monoclonal Antibody [clone: DOG1.1]

Lieferant: IMMUNOLOGIC
ILM5529-C01 ILM5529-C05 ILM5529-C1
ILM5529-C01EA 112 EUR
ILM5529-C01 ILM5529-C05 ILM5529-C1
Anti-ANO1 Mouse Monoclonal Antibody [clone: DOG1.1]
Antikörper
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST’s), KIT signaling-driven mesenchymal tumors of the GI tract. It is rarely expressed in other soft tissue tumors. Immunoreactivity has been reported in 97.8 percent of scorable GIST’s, including all KIT negative GIST’s. Overexpression has been suggested to aid in the identification of GISTs, including platelet-derived growth factor receptor alpha mutants that fail to express KIT antigen.

  • Control: Gastrointestinal stromal tumor (GIST) or testicular germ cell tumor
  • Dilution Range: 1:100-1:500 for immunohistochemical staining

Pretreatment: Heat induced epitope retrieval in 10 mM citrate buffer, pH 6,0 or in 50 mM Tris buffer pH 9,5 for 20 minutes is required for immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.

Type: Primary
Antigen: ANO1
Clonality: Monoclonal
Clone: DOG1.1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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