Anti-CYP1A2 Mouse Monoclonal Antibody [clone: UMAB105]

Lieferant: OriGene
UM500073CF
ORIGUM500073CFEA 912 EUR
ORIGUM500073CF
Anti-CYP1A2 Mouse Monoclonal Antibody [clone: UMAB105]
Antikörper
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Protein Families: Druggable Genome, P450, Transmembrane

Protein Pathways: Caffeine metabolism, Drug metabolism - cytochrome P450, Linoleic acid metabolism,
Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tryptophan metabolism

Recommended dilution: IHC 1:100

Type: Primary
Antigen:
Clonality: Monoclonal
Clone: UMAB105
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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