Human recombinant UFM1 activating enzyme (from E. coli)
Lieferant: ProSci Inc.
UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognised as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. UBA5 is located primarily in cytoplasm, while it generally localises to the nucleus in presence of SUMO2.
Fusion-Tag: N-6 His tag
This recombinant protein can be used for biological assays. For research use only.
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