Anti-KRT Mouse Monoclonal Antibody [clone: LU5]

Lieferant: IMMUNOLOGIC
ILM1026-C01 ILM1026-C05 ILM1026-C1 ILM1026-R10 ILM1026-R25 S/ILM1026-R2
ILM1026-C01EA 242 EUR
ILM1026-C01 ILM1026-C05 ILM1026-C1 ILM1026-R10 ILM1026-R25 VWRKS/ILM1026-R2
Anti-KRT Mouse Monoclonal Antibody [clone: LU5]
Antikörper
Lu-5 reacts with an epitope which is common to all cytokeratins respectively with a cytokeratin-associated protein. The antigen recognized by anti-cytokeratin pan is present in all types of epithelia. It recognizes most subtypes of cytokeratins in cryofixed and paraffin sections and is ideally suited as a first order pan-epithelial marker. The epitope recognized by Lu-5 is a formalin-resistant marker of great value in tumour diagnosis, located on the surface of cytokeratin filaments. The epitope is present in most cytokeratin polypeptides of both the acidic (type I) and basic (type II) subfamily but does not occur in other cytoskeletal proteins. The epithelial specificity and the broad tissue and species crossreactivity provide an excellent probe for the differential diagnosis of epithelial versus mesenchymal tumours, large cell lymphomas and neural tumours.

  • Control: adenocarcinoma, skin and squamous carcinoma
  • Dilution Range: 1:100-1:500

Pretreatment: Protease K treatment for 10 minutes at 37 °C is required for immunohistochemical staining on formalin-fixed, paraffin embedded tissue sections.

Type: Primary
Antigen: KRT
Clonality: Monoclonal
Clone: LU5
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human
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