Anti-PECAM1 Mouse Monoclonal Antibody (Purified) [clone: JC/70A]

Lieferant: Biotium
BNUB0639-500 BNUB0639-100
BNUB0639-500EA 511 EUR
BNUB0639-500 BNUB0639-100
Anti-PECAM1 Mouse Monoclonal Antibody (Purified) [clone: JC/70A]
Antikörper
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Type: Primary
Antigen: PECAM1
Clonality: Monoclonal
Clone: JC/70A
Conjugation: Purified
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Cynomolgus monkey, Human, Rabbit
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