Anti-HLA-DRA Mouse Monoclonal Antibody (CF488A) [clone: 19-26.1]

Lieferant: Biotium
BNC881082-500 BNC881082-100
BNC881082-500EA 560 EUR
BNC881082-500 BNC881082-100
Anti-HLA-DRA Mouse Monoclonal Antibody (CF488A) [clone: 19-26.1]
Antikörper
This MAb reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

Type: Primary
Antigen: HLA-DRA
Clonality: Monoclonal
Clone: 19-26.1
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human
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