GM-6001

Lieferant: ENZO LIFE SCIENCES

BMLEI3000001 BMLEI3000005
ENZOBMLEI3000001EA 86.9 EUR
ENZOBMLEI3000001 ENZOBMLEI3000005
GM-6001
Proteine und Peptide

MMP inhibitor


  • Lyophilized solid.


Potent broad-spectrum hydroxamate inhibitor of matrix metalloproteinases (MMPs). Ki values have been reported for the following human MMPs: MMP-1 (fibroblast collagenase): 0,4 nM; MMP-2 (gelatinase A): 0,5 nM; MMP-3 (stromelysin-1): 27 nM; MMP-7 (matrilysin): 3,7 nM; MMP-8 (neutrophil collagenase): 0,1 nM; MMP-9 (gelatinase B): 0,2 nM; MMP-12 (metalloelastase): 3,6 nM; MMP-14 (MT1-MMP): 13,4 nM; MMP-26 (endometase): 0,36 nM. Also inhibits MMP-10, MMP-13, MMP-15, MMP-17, MMP-20, MMP-21, TACE, ADAM19, other ADAMs, anthrax lethal factor, neprilysin, leucine aminopeptidase, and DPPIII. Typical concentration range for use in tissue culture is 10-25 µM. This inhibitor has also been used in vivo.

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