Retinsäure all-trans ≥95%, gelber Feststoff

Lieferant: ENZO LIFE SCIENCES

Synonyme: all-trans-Retinoic acid, (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid, ATRA, Vitamin A acid, Tretinoin

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Retinsäure all-trans ≥95%, gelber Feststoff
Retinsäure

Retinoic acid receptor ligand


Retinoic acid is the active metabolite of vitamin A. It is a potent modulator of growth and differentiation exerting its effects by binding to nuclear retinoic acid receptors (RARs) which directly regulate gene expression. All trans retinoic acid binds to RAR α, β and γ subtypes with Kd values of 0.2, 0.4 and 0.2 nM respectively. RARs function as ligand-dependent transcription factors. Retinoic Acid also promotes the differentiation of mouse embryonic stem cells into adipocytes, neurons and glia in vitro. It guides development of the posterior part of the embryo.


Soluble in DMSO (25 mg/ml) or ethanol (10 mg/ml).

Formel: C₂₀H₂₈O₂
Molecular Weight: 300,44 g/mol
Lagertemperatur: Gefrierschrank
MDL: MFCD00001551
CAS-Nummer: 302-79-4
EINECS: 206-129-0
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