Parthenolide ≥97% (durch TLC)
Lieferant: ENZO LIFE SCIENCES
HDAC inhibitor
Sesquiterpene lactone. Widely used as an herbal remedy for arthritis and migraine. Has anti-inflammatory, antisecretory and spasmolytic activity. Specifically inhibits activation of NF-kappaB by preventing the degradation of IkappaBalpha and IkappaBbeta. Inhibits activation of MAP kinase (MAPK/ERK) and generation of leukotriene B4 and thromboxane B2. Potent anticancer agent. Induces apoptosis in various cancer cell lines. Specifically inhibits histone deacetylase 1 (HDAC1) without affecting other class I/II HDACs. Inhibits tubulin carboxypeptidase (TCP) activity.
Isolated from feverfew (Chrysanthemum parthenium) leaves.
Formel:
C₁₅H₂₀O₃ |
MDL:
MFCD00134592 CAS-Nummer: 20554-84-1 |
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