SMER28 (synthetisch) ≥98% (durch TLC)

Lieferant: ENZO LIFE SCIENCES
Gefahr

Synonyme: N-Allyl-6-bromoquinazolin-4-amine

BMLEI3970005 BMLEI3970025
ENZOBMLEI3970005EA 110 EUR
ENZOBMLEI3970005 ENZOBMLEI3970025
SMER28 (synthetisch) ≥98% (durch TLC)
SMER28

Small molecule inducer of autophagy important for neurodegenerative disease research.


Chemical inducer of autophagy which acts via an mTOR-independent mechanism. It increased autophagosome synthesis and enhanced the clearance of model autophagy substrates such as A53T alpha-synuclein and mutant huntingtin fragments. It reduced Aβ peptide and AAP-CTF levels in an alzheimers model and attenuated mutant huntingtin-fragment toxicity in Huntington's disease models, suggesting therapeutic potential.


Soluble in DMSO (8 mg/ml) or 100% ethanol (2 mg/ml).

Formel: C₁₁H₁₀BrN₃
Molecular Weight: 264,126 g/mol
Lagertemperatur: Gefrierschrank
MDL: MFCD02166825
CAS-Nummer: 307538-42-7
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=19178c6ec4a62c3daad860922cad6919572a2c12&vid=3403fed074ec12a0d9f0e73b459d1ac648359048&prid=web&clid=SAPDAM

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Spezifikation Testergebnisse

Source Synthetic
Purity (TLC) ≥98%

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