PP1 ≥98% (durch TLC)
Lieferant: ENZO LIFE SCIENCES AG
ENZOBMLEI2750001EA
110
EUR
ENZOBMLEI2750001
ENZOBMLEI2750005
PP1 ≥98% (durch TLC)
PP1
Src kinase inhibitor
A highly potent and selective inhibitor of Src family tyrosine kinases, IC50=5 nM for p56lck; p59fynT=6 nM; p60src=170 nM. Inhibition of Src family kinases by PP1 has been shown to: prevent a-thrombin-stimulated Akt phosphorylation, delay PAF-mediated STAT3 phosphorylation, block Zn2+-induced Ras activation, block adhesion-dependent tyrosine phosphorylation of p105HEF1 5, and inhibit HLA-DR-induced tyrosine phosphorylation without affecting the activation of ERK1/2.
Formel:
C₁₆H₁₉N₅ Molecular Weight: 281,4 g/mol |
MDL:
MFCD01076570 CAS-Nummer: 172889-26-8 |
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