Anti-CD4 Mouse Monoclonal Antibody [clone: SK3] (CF®660C)

Lieferant: Biotium
P001-660C-500 P001-660C-125
P001-660C-500EA 350 EUR
P001-660C-500 P001-660C-125
Anti-CD4 Mouse Monoclonal Antibody [clone: SK3] (CF®660C)
Antikörper
CD4 (clone SK3) is a mouse monoclonal antibody that recognizes the extracellular domain of CD4, a membrane glycoprotein of T lymphocytes. This antibody belongs to the Biotium choice list of select antibodies that have been validated and optimized in-house for optimal performance. The antibody is available conjugated to CF® Dyes and Astral™ tandem dyes. They are supplied in PBS, 0,1% BSA, 0,05% azide.

  • Recommended concentration for flow cytometry: 5 µl per million cells/0,1 ml
  • Protect fluorescent conjugates from light

CD4 interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. The majority of peripheral T-cell lymphomas are derived from the T-helper/regulatory cell subset so that most mature T-cell neoplasms are CD4/CD8.

Anti-CD4 is used in the immunohistochemical staining of lymphoproliferative disorders to evaluate tumors with CD4 aberrant expression.

Type: Primary
Antigen: CD4
Clonality: monoclonal
Clone: SK3
Conjugation: CF®660C
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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