Anti-Sca1 (Ly-6A/E) Rat Monoclonal Antibody [clone: E13-161.7] (APC)

Lieferant: STEMCELL Technologies
STMC60032AZ.1EA 164 EUR
STMC60032AZ.1 STMC60032AZ
Anti-Sca1 (Ly-6A/E) Rat Monoclonal Antibody [clone: E13-161.7] (APC)
Antikörper
Rat monoclonal IgG2a antibody against mouse Sca1 (Ly-6A/E), APC-conjugated.

  • Hematopoietic stem
  • Progenitor cells
  • Mammary cells

The E13-161.7 antibody reacts with Sca1 (Stem Cell Antigen-1 or Ly-6A/E), an 18 kDa GPI-linked protein belonging to the lymphocyte activation protein-6 (Ly-6) family. Sca1 is expressed on the surface of hematopoietic stem and progenitor cells, myeloid cells, and peripheral B and T lymphocytes. Sca1 is expressed by mice with either the Ly-6.1 or Ly-6.2 allotypes but the pattern of expression differs in the circulating cell population according to the allotype. Ly-6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) possess relatively high numbers of Sca1+ resting lymphocytes compared to Ly-6.1 strains (e.g. A, BALB/c, CBA, C3H/He, DBA/1, NZB). Sca1 expression levels are strongly upregulated in all strains upon cellular activation. Sca1 is involved in the regulation of T and B cell responses and is believed to play roles in the differentiation, proliferation, and survival of a variety of stem cells. Sca1 has emerged as a phenotypic marker of choice for identifying and isolating hematopoietic stem and progenitor cells. This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse SCA1 Biotin Positive Selection Kit (Catalog #18856).

Bitte beachten Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: Sca1 (Ly-6A/E)
Clonality: Monoclonal
Clone: E13-161.7
Conjugation: APC
Epitope:
Host: Rat
Isotype: IgG2a kappa
Reactivity: Mouse
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