Sie suchten nach: STEMCELL Technologies

Artikel-Nr: (STMC17531)

Lieferant: STEMCELL Technologies

Beschreibung: Density gradient medium.

VE: 1 * 100 mL

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Lieferant: STEMCELL Technologies

Beschreibung: Immunomagnetic isolation of untouched human CD4+ T cells.

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Lieferant: STEMCELL Technologies

Beschreibung: Immunomagnetic isolation of untouched human naïve B cells

Lieferant: STEMCELL Technologies

Beschreibung: Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD41, FITC-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Rat monoclonal IgG2b antibody against human, mouse, rhesus CD44 (tissue non-specific alkaline phosphatase), PE-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Rat monoclonal IgG2a antibody against mouse CD4, FITC-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Mouse monoclonal IgG1, kappa isotype control antibody, Alexa Fluor® 488-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD8a, PE-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD11b, PE-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Mouse monoclonal IgG1 antibody against human CD43, APC-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD11b, APC-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Hamster (Armenian) monoclonal IgG1 antibody against human, mouse, rat CD27, PE-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Mouse monoclonal IgG2a antibody against mouse CD45.2, biotin-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Rat monoclonal IgG2a antibody against mouse CD19, PE-conjugated.

Lieferant: STEMCELL Technologies

Beschreibung: Fibroblast growth factor 10 (FGF-10) is a member of the fibroblast growth factor (FGF) family predominantly expressed by mesenchymal fibroblasts during embryonic development (Emoto <i>et al.</i>; Igarashi <i>et al.</i>). It binds with high affinity to fibroblast growth factor receptor 2-IIIb (FGFR2-IIIb), and also has a weaker affinity for FGFR1-IIIb (Beer <i>et al.</i>). FGF-10 and FGF-7 have similar receptor binding properties and target cell specificities but are differentially regulated by components of the extracellular matrix (Emoto <i>et al.</i>; Igarashi <i>et al.</i>). FGF-10 has been shown to mediate epithelial-mesenchymal interactions, which are essential to lung development (Sekine et al; Ware and Matthay). FGF-10 also has a role in mobilisation and proliferation of lung-resident mesenchymal stem cells (MSCs) and protection and repair against acute lung injury (Tong <i>et al.</i>; Ware and Matthay), as well as endodermal differentiation of human pluripotent stem cells to insulin-producing pancreatic-like cells (Takeuchi <i>et al.</i>).

Lieferant: STEMCELL Technologies

Beschreibung: Interleukin 3 (IL-3) is a species-specific pleiotropic cytokine that promotes the survival and proliferation of pluripotent hematopoietic stem cells and lineage-committed progenitor cells and their differentiation into mature cells of most lineages, including mast cells, basophils, neutrophils, eosinophils, macrophages, dendritic cells, erythrocytes, and megakaryocytes (Fung <i>et al.</i>; Metcalf <i>et al.</i>; Broughton <i>et al.</i>). IL-3 is produced by activated T cells, and has a physiological role in inflammation and allergies by promoting the secretion of inflammatory mediators such as histamine, IL-4, and IL-6 by mast cells, basophils and eosinophils. The mouse IL-3 receptor consists of a unique alpha-subunit (CD123) and two beta subunits, one specific for IL-3 (βIL-3), the other shared with the receptors for IL-5 and GM-CSF (beta common chain, βc or CD131). IL-3 binding to heterodimeric receptors containing the alpha subunit and one of either beta subunits activates JAK/STAT, MAPK, and PI3K signaling pathways (Scott and Begley).