Anti-Gr-1 (Ly-6G/Ly-6C) Rat Monoclonal Antibody [clone: RB6-8C5] (PE)

Lieferant: STEMCELL Technologies
STMC60028PEEA 521 EUR
STMC60028PE STMC60028PE.1
Anti-Gr-1 (Ly-6G/Ly-6C) Rat Monoclonal Antibody [clone: RB6-8C5] (PE)
Antikörper
Rat monoclonal IgG2b antibody against mouse Gr-1 (Ly-6G/Ly-6C), PE-conjugated.

  • Granulocytes
  • Subsets
  • Monocytes
  • Myeloid cells

The RB6-8C5 antibody reacts with the structurally related murine Ly-6G (21 - 25 kDa) and Ly-6C (14 - 16 kDa) GPI-anchored proteins, which together comprise the granulocyte receptor-1 antigen (Gr-1). Gr-1 is expressed on monocytes, neutrophils, subsets of macrophages, plasmacytoid dendritic cells, and T cells. Monocytes in the bone marrow transiently express Gr-1 during development and the expression level is strongly correlated with granulocyte differentiation and maturation. In the periphery Gr-1 is found predominantly on neutrophils and is a useful marker for these cells. Whereas the RB6-8C5 binds to both Ly-6G and Ly-6C, another commonly used anti-Gr-1 antibody, clone 1A8, binds specifically to Ly-6G. It has been reported that the 1A8 antibody detects Ly-6G-expressing granulocytes in peripheral blood, whereas the RB6-8C5 antibody also binds to Ly-6C-expressing lymphocytes, monocytes and dendritic cells. This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse Neutrophil Enrichment Kit (Catalog #19762).

Bitte beachten Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: Gr-1 (Ly-6G/Ly-6C)
Clonality: Monoclonal
Clone: RB6-8C5
Conjugation: PE
Epitope:
Host: Rat
Isotype: IgG2b kappa
Reactivity: Mouse
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