Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD25, biotin-conjugated.
- B cells
- T cells
- T cells Regulatory
The BC96 antibody reacts with human CD25, a 55 kDa type I integral transmembrane glycoprotein. CD25 is involved in the activation and proliferation of lymphocytes and can be used in the identification of T cell subsets in viral infections like HIV and HTLV. CD25 is present on activated T and B cells, monocytes, macrophages, and regulatory T cells. Expression of CD25, together with CD4 and FOXP3, is considered a phenotypic signature for regulatory T cells. CD25 has a low affinity for its IL-2 ligand but associates with IL-2 receptor β (CD122) and common γ (CD132) chains to form a high affinity IL-2 receptor.
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Type:
Antigen: CD25
Clonality: Monoclonal
Clone: BC96
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Baboon, Chimpanzee, Cynomolgus monkey, Human, Macaque, Rhesus monkey