7-Aminoactinomycin (7-AAD) Zell-Lebensfähigkeits-Farbe

Lieferant: STEMCELL Technologies

Synonyme: 2,7-Diamino-N,N'-bis[(6S,9R,10S,13R,18aS)-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4,6-dimethyl-3-oxo-3H-phenox azine-1,9-dicarboxamide, Actinomy, 7-Aminoactinomycin D, NSC-239759, NSC 239759, 2,7-diamino-4,6-dimethyl-3-oxo-1-N,9-N-bis[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide, 7-AAD

75001 75001.1
STMC75001EA 158 EUR
STMC75001 STMC75001.1
7-Aminoactinomycin (7-AAD) Zell-Lebensfähigkeits-Farbe
7-Aminoactinomycin D (7-AAD)

7‐AAD (7‐Aminoactinomycin D) is a fluorescent cell viability dye which is excluded from live cells with intact membranes but penetrates dead or damaged cells and binds to double‐stranded DNA with high affinity by intercalating between GC base pairs.


  • Cell viability dye (DNA-labeling dye)


It is often used as an alternative to propidium iodide (PI; Catalog #75002) to differentiate and exclude non-viable cells in flow cytometric analyses, and can be excited using 488 nm (blue), 532 nm (green), and 561 nm (yellow-green) laser lines. Compared to PI, 7-AAD offers the advantage of having minimal overlap in its emission spectra with mostly blue and green, and many red fluorophores, including the commonly used phycoerythrin (PE) and fluorescein isothiocyanate (FITC). 7‐AAD is also used in DNA fluorescence imaging applications to discriminate early and late stages of apoptosis, to study cell‐mediated cytotoxicity, and for chromosome banding analysis. 7‐AAD has been found to exhibit antibacterial properties and exhibits growth‐inhibitory activity against certain types of leukemia and sarcoma.


Bitte beachten Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Formel: C₆₂H₈₇N₁₃O₁₆
Molecular Weight: 1270,43 g/mol
MDL: MFCD00077295
CAS-Nummer: 7240-37-1

Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR