TriLink® N1-Methyl-Pseudouridine-5'-Triphosphate
Lieferant: TriLink BioTechnologies
N1-Methyl-Pseudouridine-5'-Triphosphate is widely used in mRNA synthesis for therapeutic and vaccine development to improve mRNA functionality. This nucleotide consists of a modified base, a ribose, and a 5′ triphosphate group.
Reduces mRNA immunostimulatory effects
Improves mRNA translation efficiency
Enhances mRNA stability
≥99% purity by AX-HPLC analysis
Provided as 100 mM in H₂O, pH 7,5
Grade: RUO
N1-Methylpseudouridine-5'-Triphosphate (N1MePsU) is a modified NTP for incorporation into messenger RNAs (mRNA) using an enzyme such as T7 RNA Polymerase. Modified uridines such as N1-methylpseudouridine, 5-methoxyuridine, and pseudouridine can reduce unwanted immunogenic response and enhance translational efficiency of mRNAs. These properties can result in safer mRNA and increased protein expression.
Bitte beachten Item will be delivered at or below −20 °C and should be stored at or below −20 °C.
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