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Product Image-AATB15259

Amplite® Fluorimetric Total NADP and NADPH Assay Kit *Red Fluorescence*

Artikel-Nr: (AATB15259)
Lieferant: AAT BIOQUEST
Beschreibung: Nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP+) are two important cofactors found in cells.
VE: 1 * 400 Tests

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Product Image-AATB15296

Cell Meter™ Intracellular NADH/NADPH Flow Cytometric Analysis Kit *Deep Red Fluorescence*

Artikel-Nr: (AATB15296)
Lieferant: AAT BIOQUEST
Beschreibung: The detection of intracellular dihydronicotinamide adenine dinucleotide NADH and its phosphate ester NADPH is important for disease diagnostics and drug discovery.
VE: 1 * 100 Tests

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Product Image-PRSI27-163

Anti-APRT Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI27-163)
Lieferant: ProSci Inc.
Beschreibung: Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
VE: 1 * 50 µG
Image Unavailable-481915-1

NAD+ lithium salt ≥90% (durch enzymatische Reinheit), Calbiochem®

Artikel-Nr: (481915-1)
Lieferant: Merck Millipore (Calbiochem‎)
Beschreibung: A major electron acceptor molecule in biological oxidations.
VE: 1 * 1 g

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Product Image-AATB15290

Cell Meter™ Intracellular NADH/NADPH Fluorescence Imaging Kit *Red Fluorescence*

Artikel-Nr: (AATB15290)
Lieferant: AAT BIOQUEST
Beschreibung: The detection of intracellular dihydronicotinamide adenine dinucleotide NADH and its phosphate ester NADPH is important for disease diagnostics and drug discovery.
VE: 1 * 100 Tests

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Product Image-AATB15295

Cell Meter™ Intracellular NADH/NADPH Fluorescence Imaging Kit *Deep Red Fluorescence*

Artikel-Nr: (AATB15295)
Lieferant: AAT BIOQUEST
Beschreibung: The detection of intracellular dihydronicotinamide adenine dinucleotide NADH and its phosphate ester NADPH is important for disease diagnostics and drug discovery.
VE: 1 * 100 Tests

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Product Image-AATB15291

Cell Meter™ Intracellular NADH/NADPH Flow Cytometric Analysis Kit *Red Fluorescence*

Artikel-Nr: (AATB15291)
Lieferant: AAT BIOQUEST
Beschreibung: The detection of intracellular dihydronicotinamide adenine dinucleotide NADH and its phosphate ester NADPH is important for disease diagnostics and drug discovery.
VE: 1 * 100 Tests

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Product Image-AATB15275

Amplite® Kolorimetrisches Gesamt-NAD- und NADH-Assay-Kit

Lieferant: AAT BIOQUEST
Beschreibung: Nicotinamidadenindinukleotid (NAD⁺) und Nicotinamidadenindinukleotidphosphat (NADP⁺) sind zwei wichtige Co-Faktoren, die in Zellen vorkommen.

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Image Unavailable-PRSI91-237

Human recombinant QAPRTase (from E. coli)

Artikel-Nr: (PRSI91-237)
Lieferant: ProSci Inc.
Beschreibung: Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quinolinic Acid (QA). The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.
VE: 1 * 50 µG
Product Image-PRSI29-725

Anti-NAMPT Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI29-725)
Lieferant: ProSci Inc.
Beschreibung: PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
VE: 1 * 100 µG
Product Image-BSBTPB10009

Anti-NAMPT Rabbit Polyclonal Antibody

Artikel-Nr: (BSBTPB10009)
Lieferant: BosterBio
Beschreibung: Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme that in humans is encoded by the PBEF1 gene. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.
VE: 1 * 100 µG
Product Image-PRSI29-726

Anti-NAMPT Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI29-726)
Lieferant: ProSci Inc.
Beschreibung: PBEF1 catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
VE: 1 * 100 µG
Product Image-PRSI5007

Anti-GAPDH Chicken Polyclonal Antibody

Artikel-Nr: (PRSI5007)
Lieferant: ProSci Inc.
Beschreibung: GAPDH Antibody: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export. GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer's and Huntington's disease. GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
VE: 1 * 100 µG
Product Image-PRSI3781

Anti-GAPDH Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI3781)
Lieferant: ProSci Inc.
Beschreibung: GAPDH Antibody: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export. GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer's and Huntington's disease. GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
VE: 1 * 100 µG
Image Unavailable-BOSSBS-5915R-CY5.5

Anti-MBD1 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-5915R-CY5.5)
Lieferant: Bioss
Beschreibung: DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
VE: 1 * 100 µl
Product Image-PRSI5003

Anti-GAPDH Chicken Polyclonal Antibody

Artikel-Nr: (PRSI5003)
Lieferant: ProSci Inc.
Beschreibung: GAPDH Antibody: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export. GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer's and Huntington's disease. GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
VE: 1 * 100 µG
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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