Sie suchten nach: 5-Azacytidine

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5-Azacytidine 99%

Lieferant: Thermo Scientific

Beschreibung: CAS No.: 320-67-2

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5-Aza-2'-deoxycytidine ≥98% (durch HPLC)

Artikel-Nr: (ENZOALX480096M005)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: DNA methyltransferase inhibitor

VE: 1 * 5 mg

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5-Aza-2'-deoxycytidine 98%

Lieferant: Thermo Scientific

Beschreibung: Appearance: White to off-white Powder

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5-Aza-2'-deoxycytidine freie Base

Lieferant: Apollo Scientific

Beschreibung: 5-Aza-2'-deoxycytidine freie Base

Beschreibung: 5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.

5-Aza-2'-deoxycytidine, weißes kristallines Pulver

Lieferant: MP Biomedicals

Beschreibung: 5-Aza-2'-deoxycytidine is an epigenetic modifier that inhibits DNA methyltransferase activity which results in DNA demethylation (hypomethylation) and gene activation by remodeling "opening" chromatin. Genes are synergistically reactivated when demethylation is combined with histone hyperacetylation.

Human Recombinant PDGF-AB

Lieferant: STEMCELL Technologies

Beschreibung: Platelet-derived growth factor (PDGF) is a dimeric glycoprotein consisting of two disulfide bridge-stabilized polypeptide chains, A and B, which are assembled as heterodimers (PDGF-AB) or homodimers (PDGF-AA and PDGF-BB) (Fretto et al.; Westermark and Heldin). PDGF signals through the receptor tyrosine kinases PDGFRalpha and PDGFRbeta. It has been shown that PDGF-induced migration involves signaling pathways involving MEK/ERK, EGFR, Src, and PI3K/AKT (Kim et al.). PDGF is a potent mitogen for cells of mesenchymal origin- like fibroblasts, glial cells, and vascular smooth muscle cells. PDGF has been implicated in pathogenesis of atherosclerosis, glomerulonephritis, cancer, and in the contraction of vascular smooth muscle cells of rat aortic tissues (Fretto et al.; Sachinidis et al.). It has been shown that PDGF-AB together with 5-Azacytidine (Catalog #72012), induces the conversion of mature bone and fat cells into tissue-regenerative multipotent stem cells (Chandrakanthan et al.).